"Their work has provided fundamental knowledge of how a living cell functions and is, for instance, used for the development of new cancer treatments," the Royal Swedish Academy of Sciences said in a statement awarding the 8 million Swedish crowns ($969,000)
Thousands of spontaneous changes to a cell's genome occur on a daily basis while radiation, free radicals and carcinogenic substances can also damage DNA.
To keep genetic materials from disintegrating, a range of molecular systems monitor and repair DNA, in processes that the three award-winning scientists all helped map out, opening the door to applications such as new cancer treatments.
Lindahl works at Britain's Francis Crick Institute and Clare Hall Laboratory, while Modrich is a researcher at the Howard Hughes Medical Institute and Duke University School of Medicine in the United States.
Sancar, who has US and Turkish citizenship, is a professor at the University of North Carolina in the United States, according to bdnews24.com.
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